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Recently there is a focus on the antioxidants as adjuvant treatment of polycystic ovary syndrome [PCOS], the most endocrinopathy in reproductive age women. The aim of this review is answer to the question whether antioxidants are effective for managing of hormonal and metabolic problems in women with PCOS based on first degree evidences from Iran. A systematic review of clinical trials was done in Persian and international databases including PubMed, Scientific Information Database, Google Scholar, Iran Medex, and Magiran up to 2013. Keywords were including polycystic ovary syndrome, Iran, vitamin, antioxidant. From 440 potential studies found electronically, 11 studies; including 444 women in intervention and 390 women in control groups. Intervention in three studies was Calcium-vitamin D or calcitriol; in three studies was omega-3 fatty acids; in two studies was N-acetyl cysteine; in one study was folic acid; in one study was Zinc; and in one study was Soy. Finally, 11 studies that were relevant and met the inclusion criteria reviewed. There were 7 studies in English and 4 studies in Persian. We couldn't include all studies because all full texts were not accessible. The results showed that antioxidants and vitamins have positive effects on management of PCOS women. Although it seems more studies is necessary in this field
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Polycystic ovary syndrome [PCOS] is a common disorder of infertility which affects more than 100 million women. It is characterized by chronic anovulation, hyper androgenism and obesity. PCOS is also associated with oxidative stress changes. Here, we aimed to investigate the level of antioxidants and oxidative stress in Iranian women with PCOS as a predictive factor for cardiovascular disease for the first time in Iran. In this cross sectional study 30 women with PCOS and 30 healthy women were included. C-reactive protein, serum insulin, advanced oxidation protein products, and level of total antioxidants status were measured from blood samples. The levels of serum insulin, C-reactive protein, advanced oxidation protein products were significantly increased in women with PCOS compared with healthy women but there was a decrease in level of total antioxidants status in PCOS women. These changes show that oxidative stress contributes to PCOS and the decrease of antioxidants leads to increase of oxidation products contributing to PCOS
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Domestic violence is an individual and social damage, which is affected by personality traits and can cause a crisis for the mental health of individuals; thus, the present study aimed to investigating personality traits and its impact on mental health of battered women in Tehran, 2013. In this cross-sectional study, 196 married women who referred to Tehran Legal Medicine Center in 2013 were selected based on simple sampling method, and then were studied based on General Health Questionnaire [GHQ-28] and the NEO Five Factor Inventory [NEO-FFI]. In this cross-sectional study, the data were analyzed with the Pearson Correlation Test using the SPSS-16.The present study revealed that statistically mental health has a significant and positive correlation with neuroticism personality trait [r=0.318, P<0.001], while it has a significant but negative correlation with extraversion personality trait [r=-0.280, P<0.001], agreeableness [r=-0.201, P=0.002], and conscientiousness [r=-0.265, P=0.001]. Although mental disorder on the part of battered women paves the way for violence against them, learning personality traits along with individual and social factors among women can significantly contribute to prevention, screening and necessary treatments by experts and authorities
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To compare self-confidence in woman with and without PCOS according to their ages. This comparative study was conducted on 400 women [100 with and 300 without PCOS] in clinics of Shahid Akbar-Abadi and Firouzgar Hospitals, from July 2012 to February 2013. SPSS-16 used for statistical analysis [SPSS; SPSS Inc., Chicago, IL, USA]. This study showed 98% of PCOS and 93% in non-PCOS groups had average self-confidence with scores of 15-25. None of women in PCOS group and 6.7% of non-PCOS group had high self-confidence [score>25]. There was a significant difference between two groups in term of self-confidence level [p< 0.001]. There was no significant difference in self-confidence between age group 30 in both group, but in PCOS group, self-confidence were significantly higher in both age group under 30 [p<0.0001] and 30 and higher [p<0.0001]. Impaired self-confidence in PCOS groups [under 30 and 30 and higher age groups] in comparison with related value of non-PCOS group shows that mental health status in women with PCOS requires urgent psychological attention and support
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Objective: To assess the relationship between maternal UTI during pregnancy and neonatal UTI
Materials and methods: This cross-sectional study included eighty neonates referred to Ali-e-Asghar Hospital, Tehran, Iran, in 2011. The participants were divided into the study [with diagnosis of UTI; n = 40] and the control [without this type of infection; n = 40] groups. The mothers were asked about the history of UTI during pregnancy, and if the response was positive, the trimester in which UTI had occurred. Urinalysis and urine culture were carried out for all neonates
Results: Overall, 14.9% of neonates had mothers with a positive history of UTI during their pregnancy [4.4%, 6.1%, and 4.4% during the 1[st], 2[nd], and 3[rd] trimesters, respectively]. A significant relationship was detected between the occurrence of UTI in neonates and maternal UTI, so that the overall prevalence of UTI among neonates of affected mothers was significantly higher than that observed among non-infected mothers [30.0% versus 6.8%; p = 0.001]. Maternal UTI resulted in 5.9-fold increased risk of neonatal UTI. In UTI group, the most common bacterial etiologies of UTI were Escherichia coli [65.9%], followed by Klebsiella [14.6%] and Staphylococci [9.8%]
Conclusion: Our findings confirmed the association between the history of UTI in mother and occurrence of UTI in neonate, emphasizing to pay more attention for assessing and managing UTI in neonates in order to reduce the related complications
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Today there are abounding collected data in cases of various diseases in medical sciences. Physicians can access new findings about diseases and procedures in dealing with them by probing these data. This study was performed to predict stroke incidence. This study was carried out in Esfahan Al-Zahra and Mashhad Ghaem hospitals during 2010-2011. Information on 807 healthy and sick subjects was collected using a standard checklist that contains 50 risk factors for stroke such as history of cardiovascular disease, diabetes, hyperlipidemia, smoking and alcohol consumption. For analyzing data we used data mining techniques, K-nearest neighbor and C4.5 decision tree using WEKA. The accuracy of the C4.5 decision tree algorithm and K-nearest neighbor in predicting stroke was 95.42% and 94.18%, respectively. The two algorithms, C4.5 decision tree algorithm and K-nearest neighbor, can be used in order to predict stroke in high risk groups
Subject(s)
Humans , Predictive Value of Tests , Data Mining , Decision Trees , Stroke/diagnosis , Risk FactorsABSTRACT
The purpose of this study was to determine the level of knowledge of folic acid supplementation amongst Iranian pregnant women. We selected 322 women through simple randomized method in a cross section study. Data was gathered on the base of questionnaire and interview. Statistical analysis was performed using SPSS software. The value of p<0.05 was considered as significant level. The obtained information revealed that 7.8% with high level of knowledge, 43.8% with intermediate level, 30.4% with low level knowledge, and 18% with no knowledge. Hospitals and health centers are two major sources for promoting popular awareness about folic acid. There is a significant relationship between the knowledge, education, employment, time of prenatal care beginning, age, gravidity, and sources of health information. The number of women with high level of knowledge was more among those with lower parity, higher level of education, employment, young age and looking for health information. Awareness of folic acid is low among Iranian women. The different strategies are required to elevate the knowledge about folic acid among the women in reproductive age and provide them with some information about the benefits of this supplement
Subject(s)
Humans , Female , Awareness , Knowledge , Pregnant Women , Cross-Sectional Studies , PregnancyABSTRACT
Objective[s]: This study aimed to translation and determine the reliability and validity of the Health-related quality of life for women with polycystic ovary syndrome and was done on 190 women with polycystic ovary syndrome referred to selected infertility centers of Tehran during 2010-2011
Methods: For Translation English version of PCOSQ, Forward-Backward method and to determine the reliability of the instrument, internal consistency was used. For assessing the validity of this questionnaire, Item-Scale correlation and Known groups' comparison were identified. The results were analyzed with SPSS-14
Results: The results of this study showed that Cronbach's alpha coefficient for all dimensions except menstrual problems were higher than o.7. Also, all questions showed an adequate correlation with their dimensions [r>0.4] and all domains scores except menstrual problems, regarding to BMI showed significant statistical differences [P<0.05]
Conclusion: However, it seems that Iranian version of this questionnaire is an acceptable questionnaire with adequate reliability and validity in all dimensions except for menstrual problems. For obtain better results, further studies with larger sample size and different settings are recommended
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Objective [s]: Polycystic ovary syndrome [PCOS] is a disorder of hyperandrogenemia and chronic anovulation which affects 5-10% of all women. The PCOS symptoms such as hirsutism, irregular menses, obesity and infertility are a major source of psychological morbidity and can negatively affect quality of life. In this study, we examined the health-related quality of life among Iranian women who suffering from PCOS
Study design: Quality of life was assessed in five domain separatively [menstrual disorders, hirsutism, infertility problems, emotions, and obesity] in 152 women who referred to Tehran selected infertility centers in Tehran, Iran in 2010-2011
Results: The findings showed that patients scored lower on menstrual disorders, hirsutism, infertility problems, emotions, and obesity
Conclusion: This study showed that menstural disorder is the most important domain that affects Iranian women's HR-QoL
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The aim of this study was to estimate the frequency of preterm birth [PTB] and premature rapture of membranes [PROM] and their associations with maternal factors. This cross sectional study was carried out at Akbar-Abadi hospital in Tehran during January 2009-Aprile 2010. Four hundred sixty six primiparous women with gestational age more than 20 weeks and singleton pregnancy were enrolled in the study. Data were analyzed using SPSS-16. P<0.05 was considered as being significant. maternal age, maternal height, maternal education, pre-pregnancy maternal weight, occupation and smoking during pregnancy were compared between two groups [with or without PTB/PROM]. This study shows the incidence of PTB to be 27.9% and PROM to be 34.7%. None of maternal factors in this study showed significant relation with PTB. Significant relation was found between maternal age and PROM, p<0.001. PROM was related to PTB significantly [p=0.040]. Findings highlighted the importance of maternal age as a cause of adverse pregnancy outcomes. Since this study showed PROM and PTB to be two common adverse pregnancy outcomes in Iran assembling appropriate services can lead mothers to improved pregnancy outcomes especially among older pregnant women
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Although numerous studies have depicted the association between adverse pregnancy outcomes and the future fertility status, this relationship has not been clearly outlined. A positive past medical history for adverse pregnancy outcomes, such as induced abortion, ectopic pregnancy, postpartum infection, premature rupture of membranes can affects women's fertility prospects. The main goal of this study was to determine the relationship between previous pregnancy outcomes and secondary infertility. This retrospective case-control study was done on 182 [92 infertile and 90 pregnant women], 15-45 years old patients during a six-month period in 2008-2009. The study took place in Imam Djavad Hospital in Naghan, Chaharmahal Bakhtiari province, in Iran. The outcomes of prior pregnancies such as abortion, ectopic pregnancy, postpartum infection, prolonged labor, premature rupture of membranes, manual removal of the placenta and postpartum curettage were compared to those of the controls. The data were analyzed by t-test and chi-square. In the case group, induced abortion and postpartum infection were significantly higher than the control group [p<0.05]. No significant differences were found between the two groups regarding a history for spontaneous abortion, ectopic pregnancy, prolonged labor, premature rupture of membranes, manual removal of placenta or postpartum curettage. A past medical history of induced abortion and postpartum infection can negatively affects prospective pregnancy outcomes. By educating women and health care providers, we may help prevent the detrimental effects of these disease states on women's future fertility status